Webinar: Common Dilemmas in Prostate Cancer Detection and Management (2020)

August 26, 2020

Course Director: Gerald R. Andriole, Jr. MD

Course participants will:

Optimally use PSA and other biomarkers to minimize unnecessary testing and biopsy when screening men who are at average risk for prostate cancer.

Understand the principles of “risk-adapted” screening for men at elevated risk for prostate cancer based on race, family history, early in life PSA, polygenic risk scores, and specific genetic mutations (eg BRCA1/2).

Understand the roles of MRI, high frequency ultrasound and novel transperineal approaches to improve prostate biopsy.

Understand the role of PET imaging in men with prostate cancer, especially those with biochemical recurrence and the rationale for metastasis-directed therapy in these men.

Learn to treat men with locally advanced prostate cancer with multimodal approaches.

Learn how to choose and sequence hormonal, chemotherapeutic, immunologic and/or targeted approaches (eg, PARP inhibitors) in men with metastatic and castrate resistant prostate cancer.


Acknowledgements:

This educational activity is supported by independent educational grants from:

  • Astellas
  • AstraZeneca
  • Bristol-Myers Squibb
  • Genentech
  • Merck
  • Pfizer, Inc.
  • Sanofi Genzyme

Target Audience

  • Urologists
  • Residents
  • Advanced Practice Providers (Nurse Practitioners and Physician Assistants)

Learning Objectives

Upon completion of this activity, participants will be able to:

  1. Optimally use PSA and other biomarkers to minimize unnecessary testing and biopsy when screening men who are at average risk for prostate cancer.
  2. Apply the principles of “risk-adapted” screening for men at elevated risk for prostate cancer based on race, family history, early in life PSA, polygenic risk scores, and specific genetic mutations (eg BRCA1/2).
  3. Identify the roles of MRI, high frequency ultrasound and novel transperineal approaches to improve prostate biopsy.
  4. Describe the roles of MRI, high frequency ultrasound and novel transperineal approaches to improve prostate biopsy.
  5. Treat men with locally advanced prostate cancer with multimodal approaches and how to choose and sequence hormonal, chemotherapeutic, immunologic and/or targeted approaches (eg, PARP inhibitors) in men with metastatic and castrate resistant prostate cancer.
Course summary
Available credit: 
  • 1.50 AMA PRA Category 1 Credit™
  • 1.50 Non-Physician Participation
Course opens: 
07/17/2020
Course expires: 
08/26/2023
Event starts: 
08/26/2020 - 10:30am EDT
Event ends: 
08/26/2020 - 12:00pm EDT
Rating: 
0

Scientific Agenda

Welcome, Housekeeping Notes

AUA

Use of PSA in Screening and Prognosis

Anthony D’Amico MD, PhD

Professor of Radiation Oncology

Harvard Medical School

Chief of Genitourinary Radiation Oncology at Dana-Farber Cancer Center and Brigham and Women’s Hospital

Novel Biomarkers for CaP

Adam S. Kibel, MD

Professor of Surgery (Urology)

Harvard Medical School

Chief of Urologic Surgery

Brigham and Women’s Hospital

 

Optimizing Prostate Biopsy and Prostate Imaging

Gerald L. Andriole, MD

Royce Distinguished Professor of Surgery (Urology)

Chief of Urology

Washington University School of Medicine

Siteman Cancer Center

Barnes-Jewish Hospital

 

PSA in Advanced Prostate Cancer

Oliver Sartor, MD

Laborde Professor for Cancer Research

Medical Director, Tulane Cancer Center

Tulane University Medical School, New Orleans, LA

 

Q&A

All Faculty

 

WEBINAR ADJOURNS – BROADCAST ENDS 

Common Dilemmas in Prostate Cancer Detection and Management 2020) will be held virtually on Wednesday, August 26 at 10:30 AM EST.

***Instructions***

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Education Council Disclosures

PDF icon Education Council & COI Reviewer Disclosure_082620.pdf

Faculty Disclosures: PDF icon Faculty Disclosures.pdf

AUA Office of Education Staff has nothing to disclose.

 

 

Course Director(s)

Gerald Andriole, MD

has a financial relationship (Independent contractor) with Myriad Genetics;.
has a financial relationship (Other) with Blue Earth Diagnostics;.
has a financial relationship (Independent contractor) with Stratify Genomics;.
has a financial relationship (Other) with FKD Therapies;.
has a financial relationship (Other) with Progenics;.
has a financial relationship (Independent contractor) with Janssen;.
has a financial relationship (Independent contractor) with 3D Biopsy;.
Faculty(s)

Anthony D'Amico, MD, PHD

has no relevant financial relationships to disclose at this time.

Adam Kibel, MD

has a financial relationship (Other) with advantagene;.
has a financial relationship (Other) with Bristol-Myers Squibb;.
has a financial relationship (Independent contractor) with Insight Diagnositics;.
has a financial relationship (Independent contractor) with Merck;.
has a financial relationship (Independent contractor) with Profound;.
has a financial relationship (Independent contractor) with ConfirmMDx;.
has a financial relationship (Independent contractor) with Janssen;.

A. Oliver Sartor, MD

has a financial relationship (Independent contractor) with Progenics;.
has a financial relationship (Independent contractor) with Pfizer;.
has a financial relationship (Independent contractor) with Dendreon;.
has a financial relationship (Independent contractor) with Jannsen;.
has a financial relationship (Independent contractor) with Clovis;.
has a financial relationship (Independent contractor) with Bavarian Nordic;.
has a financial relationship (Independent contractor) with Advancel Accelerator Applications (AAA);.
has a financial relationship (Independent contractor) with EMD Serono;.
has a financial relationship (Independent contractor) with Myovant;.
has a financial relationship (Independent contractor) with Constellation;.
has a financial relationship (Independent contractor) with Novartis;.
has a financial relationship (Other) with Invitae;.
has a financial relationship (Independent contractor) with Endocyte;.
has a financial relationship (Independent contractor) with Myriad;.
has a financial relationship (Independent contractor) with Bristol Myers Squibb;.
has a financial relationship (Independent contractor) with Astellas;.
has a financial relationship (Independent contractor) with AstraZeneca;.
has a financial relationship (Independent contractor) with Bayer;.
has a financial relationship (Independent contractor) with Noxopharm;.

ACCREDITATION: 

The American Urological Association (AUA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION: 

The American Urological Association designates this live activity for a maximum of 1.50 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

OTHER LEARNERS: 

The AUA is not accredited to offer credit to participants who are not MDs or DOs. However, the AUA will issue documentation of participation that states that the activity was certified for AMA PRA Category 1 Credit™.

EVIDENCE BASED CONTENT: 

It is the policy of the AUA to ensure that the content contained in this CME activity is valid, fair, balanced, scientifically rigorous, and free of commercial bias.

AUA DISCLOSURE POLICY: 

All persons in a position to control the content of an educational activity (i.e., activity planners, presenters, authors) are required to disclose to the provider any relevant financial relationships with any commercial interest. The AUA must determine if the individual’s relationships may influence the educational content and resolve any conflicts of interest prior to the commencement of the educational activity. The intent of this disclosure is not to prevent individuals with relevant financial relationships from participating, but rather to provide learners information with which they can make their own judgments.

RESOLUTION OF IDENTIFIED CONFLICT OF INTEREST: 

All disclosures will be reviewed by the AUA Conflict of Interest (COI) Review Work Group for identification of conflicts of interest. The AUA COI Review Work Group, working with the program directors and/or editors, will document the mechanism(s) for management and resolution of the conflict of interest and final approval of the activity will be documented prior to implementation. Any of the mechanisms below can/will be used to resolve conflict of interest:

  • Peer review for valid, evidence-based content of all materials associated with an educational activity by the course/program director, editor, and/or AUA COI Review Work Group.
  • Limit content to evidence with no recommendations
  • Introduction of a debate format with an unbiased moderator (point-counterpoint)
  • Inclusion of moderated panel discussion
  • Publication of a parallel or rebuttal article for an article that is felt to be biased
  • Limit equipment representatives to providing logistics and operation support only in procedural demonstrations
  • Divestiture of the relationship by faculty

OFF-LABEL OR UNAPPROVED USE OF DRUGS OR DEVICES: 

The audience is advised that this continuing medical education activity may contain reference(s) to off-label or unapproved uses of drugs or devices. Please consult the prescribing information for full disclosure of approved uses.


AUA Participant Information and Policies

DISCLAIMER:

The opinions and recommendations expressed by faculty, authors and other experts whose input is included in this program are their own and do not necessarily represent the viewpoint of the AUA.

AUDIO, VIDEO AND PHOTOGRAPHIC EQUIPMENT:

The use of audio, video and other photographic recording equipment by attendees is prohibited inside AUA meetings.

REPRODUCTION PERMISSION: 

Reproduction of written materials developed for this AUA course is prohibited without the written permission from individual authors and the American Urological Association.

Available Credit

  • 1.50 AMA PRA Category 1 Credit™
  • 1.50 Non-Physician Participation
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